Uic2 antibody

Author: qfyw

August undefined, 2024

WebFlow Cytometry - APC Anti-P Glycoprotein antibody [UIC2] (ab272340) Separation of HepG2 (Human liver hepatocellular carcinoma cell line) cells (red-filled) from human peripheral whole blood cells (black-dashed) in … WebThe UIC2 antibody reacts with an external epitope of the human P-glycoprotein (P-gp). UIC2 antibody inhibits Pgp-mediated efflux and potentiates the cytotoxic action of P-gp transported drugs in MDR cells. Customers Also Viewed. Life Sciences Division Headquarters 5350 Lakeview Parkway S Drive

PE anti-human CD243 MDR-1 Antibody anti-CD243 - UIC2

WebThe drug-resistance phenotype of P-gp can be modulated by the monoclonal antibody UIC2, which specifically recognizes human P-gp in a conformation-dependent manner. Here, the purification, sequence determination and high-resolution structure of the Fab fragment of UIC2 (UIC2/Fab) are reported. WebAPC Anti-P Glycoprotein antibody [UIC2] See all P Glycoprotein primary antibodies Description APC Mouse monoclonal [UIC2] to P Glycoprotein Host species Mouse Conjugation APC. Ex: 645nm, Em: 660nm Tested … pennywort aquatic plant

Mouse anti Human CD243 (A281888) Antibodies.com

WebWithin the immune system, this molecule can be found on normal T, B, and natural killer cells, but not on monocytes. This antibody has been reported to inhibit MDR1-mediated efflux. Applications Reported: This UIC2 antibody has been reported for use in flow cytometric analysis. Web22 Jan 2013 · Product name PE Anti-P Glycoprotein antibody [UIC2] See all P Glycoprotein primary antibodies Description PE Mouse monoclonal [UIC2] to P Glycoprotein Host … WebUIC2 is a monoclonal antibody that binds to the extracellular region of ABCB1, particularly extracellular loops 1, 3 and 4 [ 29 ]. Thus, it allows for labeling of cell surface-expressed ABCB1 without disrupting the plasma membrane. pennywort control

What clinical evidence supports the use of lecanemab for …

MDR1/ABCB1 Antibody (UIC2) SCBT - Santa Cruz Biotechnology

WebTranslations in context of "méthodes se rapportant à" in French-English from Reverso Context: compositions et méthodes se rapportant à stop -1 Web13 Feb 2024 · The ABCB1-specific inhibitory antibody UIC2 was developed with the goal of increasing antitumor drug treatment efficacy (8, 9). UIC2 targets the extracellular moiety of human ABCB1 (ABCB1 H ) and has been successfully used to investigate the transport cycle of ABCB1 owing to its ability to bind the transporter during various states of the catalytic … pennyworth 1080pWeb27 Mar 2014 · Miele authored the 1997 Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products. In 1994, he … pennywort aquarium care

"WebApplications Tested: This UIC2 antibody has been pre-titrated and tested by flow cytometric analysis on multidrug resistant cell lines. This can be used at 5 µL (0.5 µg) per test. A test … " - Uic2 antibody

Uic2 antibody

MDR1/ABCB1 Antibody (UIC2) SCBT - Santa Cruz Biotechnology

Web27 Sep 2024 · UIC2 shift assay ( a) was used to evaluate the impact of verapamil, paclitaxel, and DAC-2Amide, -3Amide and -4Amide on P-gp conformation. Normalized median fluorescence intensity (MFI) upon... Web19 Sep 2014 · The UIC2 monoclonal antibody recognizes human Pgp and inhibits its drug transport activity. However, this inhibition is partial, since UIC2 binds only to 10–40% of …

Did you know?

WebBuy mouse monoclonal (UIC2) antibody to CD243 (A281888). Applications: IHC, IP and more. Reactivity: Human and Primate. ️ 100% Guarantee Web13 Feb 2024 · MDR1/ABCB1 Antibody (UIC2) is a mouse monoclonal IgG 2a κ, cited in 31 publications, provided at 200 µg/ml. recommended for detection of MDR1 P-glycoprotien of human origin by IP, IF, IHC (P) and FCM; non cross-reactive with mouse and rat tissues. available conjugated to either phycoerythrin or FITC for IF, IHC (P) and FCM.

Web24 Aug 2024 · Despite the potential clinical application of this finding, the epitopes of the three human P-gp-specific monoclonal antibodies MRK-16, UIC2 and 4E3, which bind to … WebEnter the email address you signed up with and we'll email you a reset link.

WebIntroduction On January 6, 2024, lecanemab (Leqembi) was granted accelerated approval by the United States Food and Drug Administration (FDA) for the treatment of early Alzheimer disease (AD). 1 The second in its class, lecanemab is preceded by the controversial amyloid beta-directed monoclonal antibody, aducanumab (Aduhelm). Like aducanumab, … WebThe mouse monoclonal antibody UIC2 recognizes an extracellular epitope on CD243 (MDR-1), an approximately 170 kDa ABC transporter expressed on hematopoietic stem cells, B, …

WebInvitrogen Anti-P-Glycoprotein Monoclonal (UIC2), Catalog # MA5-44031. Tested in Immunohistochemistry (Frozen) (IHC (F)), Immunohistochemistry (Paraffin) (IHC (P)), …

WebClone UIC2 is a strong inhibitor of CD243-mediated efflux and of the resistance of MDR cells to CD243 transported cytotoxic drugs. Clone UIC2 can be used in a shift assay to … pennywort extractWebApplications Tested: This UIC2 antibody has been pre-titrated and tested by flow cytometric analysis on multidrug resistant cell lines. This can be used at 5 µL (0.5 µg) per test. A test is defined as the amount (µg) of antibody that will stain a … pennywort flowerWebUIC2 is a mouse monoclonal antibody directed against the extracellular conformational epitope of P-glycoprotein (Pgp). This antibody can be used in flow cytometry, … to char for date in sqlWeb19 Sep 2014 · The UIC2 monoclonal antibody recognizes human Pgp and inhibits its drug transport activity. However, this inhibition is partial, since UIC2 binds only to 10-40% of cell surface Pgps, while the rest becomes accessible to this antibody only in the presence of certain substrates or modulators (e.g. cyclosporine A (CsA)). to char fecha oracleWebThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. Application FC - Quality tested. Recommended Usage Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use ... pennywort edibleWebBuy mouse monoclonal (UIC2) antibody to CD243 (A121698). Validated Applications: Flow Cytometry. Reactivity: Human. ️ Low Prices ️ 100% Guarantee to char formatWeb13 Feb 2024 · Datasheets. MDR1/ABCB1 Antibody (UIC2) is a mouse monoclonal IgG 2a κ, cited in 31 publications, provided at 200 µg/ml. raised against MDR1 of human origin. … pennywort ground cover