WebCytarabine is indicated for remission induction in patients with acute myelocytic leukemia. It is more effective when it is combined with anthracyclines. Low-dose Ara-C is used in the treatment of chronic myelogenous leukemia in combination with interferon-α. ... Patients with renal failure are at increased risk of developing the syndrome ... WebCytarabine, a synthetic pyrimidine nucleoside, is converted intracellularly, primarily by deoxycytidine kinase, to active ... a serious disease for which safer drugs cannot be used or are ineffective). ... renal/genitourinary renal dysfunction : urinary retention (< 2%) 4 sexual/reproductive . function : germ cell toxicity; reversible and ...
The association between high-dose cytarabine …
WebSep 21, 2024 · Cytarabine syndrome reported; may manifest as fever, myalgia, bone pain, maculopapular rash, conjunctivitis, malaise, and occasionally chest pain. Generally occurs 6–12 hours after administration of conventional cytarabine. Corticosteroids are beneficial in treatment and prevention. WebLow-dose cytarabine-induced hepatic and renal dysfunction in a patient with myelodysplastic syndrome. We report a 49-year-old female patient with secondary … ctht
Allopurinol/cytarabine SpringerLink
WebApr 14, 2024 · Africa, particularly sub-Sharan Africa (SSA), faces major challenges in respect to chronic kidney disease (CKD). There is a rising prevalence due to the combined effects of hypertension, diabetes, and human immunodeficiency virus (HIV) (and the interaction between them) and the effect of apolipoprotein L1 (APOL1) variants on the … WebKidney disease. Infectious disease. Sepsis "Cytarabine syndrome": fever, myalgia, bone pain, rash, conjunctivitis, malaise ... leukopenia, thrombocytopenia), liver disease, … WebOct 28, 2024 · Kidney disease or; Liver disease—Effects of cytarabine may be increased because of slower removal from the body; Proper use of cytarabine. Cytarabine is sometimes given together with certain other medicines. If you are using a combination of medicines, it is important that you receive each one at the proper time. If you are taking … earth layers inner core